
Estimates of the number of molecules in each library prepared from 3 µL DNA extract binned by size. (A) Total number of molecules (note that peaks below 20 bp are due to artifacts from library preparation). (B) Number of ‘informative’ molecules, i.e., molecules producing sequences that can be aligned to the genome of a close relative. Numbers for the libraries prepared from buffer exchange extracts were multiplied by 2.5 to compensate for the smaller volume of lysate used. See Figure 2 legend for sample S1–S7 identities.











