YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment

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Figure 1.
Figure 1.

CTCF binding and expression decrease during neural development. (A) Number of CTCF ChIP-seq peaks called across the ES 2i, ES serum, and NPC cellular states. (B) Number of CTCF ChIP-seq peaks across several mouse ENCODE brain tissues (Shen et al. 2012). (C) Relative CTCF gene expression across three developmental cell types (error bars represent 1 SD from mean across two replicates). (D) Normalized CTCF gene expression (FPKM) across mouse ENCODE brain tissues (error bars represent 1 SD from mean across two replicates) (Shen et al. 2012).

This Article

  1. Genome Res. 27: 1139-1152

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