Figure 5.
RNA editing in miR-200b redirects the target genes. (A) Sequence motif identified in 3′ UTRs of down-regulated genes upon transfection with WT miR-200b mimics (vs. negative control), corresponding to seed match of WT miR-200b. (B) Sequence motif identified in 3′ UTRs of down-regulated genes upon transfection with edited miR-200b mimics (vs. negative control), corresponding to seed match of edited miR-200b. (C) High-confidence predicted target genes of WT miR-200b and edited miR-200b by integrating gene expression and sequence motif data.
