Figure 4.
The conversion tracts of paired-nicks–induced HDR. (A–D) The conversion tracts of paired-nicks–induced HDR using S (A,B) and AS ODNs (C,D). The conversion tracts were compiled by overlaying the retention frequency of each SNP in both 6SNP_A and 6SNP_B donors (Fig. 2F). The positions of the SNPs and predicted genomic lesions are labeled in reference to the center of the chromophore sequence. All schematic elements are colored as in the legend of Figure 2.
