Figure 6.
The circadian clock enables nutrient-independent Pol III recruitment. (A) MVA plot showing the average of ZT02 and ZT10 scores on the x-axis and the difference of ZT10 – ZT02 scores on the y-axis. Large black dots represent genes changing between day and night with a P-value <0.05, as calculated with limma. (B) As in A, but for Arntl KO samples. (C) As in A, but for the CF samples. (D) As in A, but for the Maf1 KO samples. (E) Regulation of Pol III gene occupancy by the core clock, which activates Pol III before the night feeding period, and by the feeding response, which activates TORC1, which itself inactivates the MAF1 repressor.
