Cytosine modifications modulate the chromatin architecture of transcriptional enhancers

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Gain of 5hmC at MEIS1-bound enhancers is followed by chromatin opening and MEIS1 binding. (A) Heat maps of MEIS1 and FAIRE differential signals (ΔS) during P19 cell differentiation in clusterized MEIS1 binding regions. Blue: decrease; red: increase. (B) Dynamic average profiles of 5hmC, chromatin opening, and MEIS1 recruitment at clusters shown in A.

This Article

  1. Published in Advance April 10, 2017, doi: 10.1101/gr.211466.116 Genome Res. 27: 947-958

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research