Harmen J.G. van de Werken; Josien C. Haan; Yana Feodorova; Dominika Bijos; An Weuts; Koen Theunis; Sjoerd J.B. Holwerda; Wouter Meuleman; Ludo Pagie; Katharina Thanisch; Parveen Kumar; Heinrich Leonhardt; Peter Marynen; Bas van Steensel; Thierry Voet; Wouter de Laat; Irina Solovei; Boris Joffe

Small chromosomal regions position themselves autonomously according to their chromatin class

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Figure 6.

Nuclear lamina interactions of L-HAC in comparison to hHOR and mHOR. (A) DamID profile of nuclear lamina (NL) interactions (Dam-Lamin B1/Dam log₂ ratio) along the L-HAC in mouse A9 cells and along the corresponding region of human Chromosome 1 (HSA1) in human lung fibroblasts (Tig3 Fb; data from Guelen et al. 2008). (B) DamID profile along the mHOR on mouse Chromosome 3 (MMU3) in A9 cells carrying L-HAC. Annotation tracks are as in Figures 1 and 2.