
Nucleosome remodeling occurs in genes whose expression is down-regulated or up-regulated during development. Normalized read midpoint frequencies in growing-stage (black) and loose-mound–stage (red) WT cells for developmentally remodeled genes aligned to the midpoint of the first defined nucleosome in growing WT cells. (A) Remodeled genes whose expression is down-regulated from growth to the loose-mound stage (see Supplemental Fig. S6). (B) Remodeled genes whose expression is up-regulated from growth to the loose-mound stage (see Supplemental Fig. S6).











