A-to-I RNA editing promotes developmental stage–specific gene and lncRNA expression

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Figure 5.
Figure 5.

Pseudogenes do not exhibit down-regulation in ADAR and RNAi mutants at the embryo stage. Log scale plots comparing gene expression of wild-type (N2) worms to adr-1(−/−);adr-2(−/−);rde-1(−/−) (A) or adr-1(−/−);adr-2(−/−);rde-4(−/−) (B) mutant worms at the embryo stage of development. (C) Log scale plot comparing primary siRNA expression of wild-type (N2) worms to adr-1(−/−);adr-2(−/−) mutant worms. Every dot represents a gene. The red line is the regression line for all genes. Purple dots indicate pseudogenes and the regression line is presented in purple.

This Article

  1. Published in Advance December 28, 2016, doi: 10.1101/gr.211169.116 Genome Res. 27: 462-470

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