Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types

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Figure 2.
Figure 2.

(A) Multidimensional scaling of zebrafish lck+ single-cell transcriptomes. Expression of known immune marker genes is depicted (using an expression threshold of five transcripts per million [TPM]). High granularity depicts cells with high side scattered light (top 5%). (B) Expression of T, NK-like, and myeloid cells’ transcriptional signatures (colors) together with the results of whole-transcriptome unsupervised clustering (shapes). (C) Distribution of side scattered light (proxy for cellular granularity) for cells in each cluster.

This Article

  1. Genome Res. 27: 451-461

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