Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 1.
Figure 1.

The gene expression in the single-cell experiment. (A) Expression of the top 300 genes with greater than twofold differential expression between clusters that were previously established by hierarchical clustering. x-axis: The cells with roman II denote the second batch of cells. Note that the cells from both batches are represented in all clusters. (B) Known trophoblast markers are shown separately, with general trophoblast markers in black, extravillous trophoblasts in blue, and cytotrophoblast-specific expression in gray. (C) First three principal components based on 300 marker genes (full PCA in Supplemental Fig. S8). Clusters correspond to the clustering in the heat map in A.

This Article

  1. Genome Res. 27: 349-361

Preprint Server