Comparative analyses of super-enhancers reveal conserved elements in vertebrate genomes

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Figure 3.
Figure 3.

Cell and tissue specificity of vertebrate typical enhancers and SEs. (A) Distribution of H3K27ac at selected genes (genomic position represented on the x-axis) in both pluripotent state and adult brain of zebrafish, mouse, and human (raw tag counts represented on the y-axis). Typical enhancers and SEs are denoted by gray bars and red bars, respectively. (B) Chow-Ruskey diagrams representing the overlap between pluripotent state (orange), brain (green), heart (purple), intestine (red), and testis (blue) typical enhancers and SEs in zebrafish. Color-coded tables show the percentages of cell- or tissue-specific and nonspecific regions for each data set.

This Article

  1. Genome Res. 27: 259-268

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