Vladimir B. Seplyarskiy; Maria A. Andrianova; Georgii A. Bazykin

APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context

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Figure 2.

APOBEC3A/B-induced mutations occur preferentially on the nontemplate strand. Color-coded log₂ of the ratio of densities of rare polymorphisms on the nontemplate strand (A) or the template strand (B) and intergenic regions, or of the ratio of densities of rare polymorphisms on the nontemplate and template strands (C). Mutations in the TpCpW→K context that may be associated with APOBEC3A/B activity are in green boxes.