Co-expression networks reveal the tissue-specific regulation of transcription and splicing

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Figure 6.
Figure 6.

Association of local genetic variants with distant network neighbors. (A) Enrichment of association between rs113305055, a genetic variant near a cross-tissue TWN hub TMEM160, with all isoform ratios genome-wide in artery–tibial. (B) Enrichment of associations between local genetic variants (either the top cis-eVariant or any variant within 20 kb) of each gene, and network neighbors in the TSNs. (C) Enrichment of association between rs115419420, a genetic variant local to CRELD1, with all isoform ratios in skeletal muscle.

This Article

  1. Published in Advance October 11, 2017, doi: 10.1101/gr.216721.116 Genome Res. 27: 1843-1858

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