Nascent RNA sequencing reveals a dynamic global transcriptional response at genes and enhancers to the natural medicinal compound celastrol

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Figure 6.
Figure 6.

Celastrol down-regulates most of the same genes as heat shock but up-regulates many different genes. (A) Venn diagram of genes that are up-regulated after 30 min of heat shock vs. after 40 min of celastrol treatment. (B) Venn diagram of genes that are down-regulated after 30 min of heat shock vs. after 40 min of celastrol treatment.

This Article

  1. Published in Advance October 12, 2017, doi: 10.1101/gr.222935.117 Genome Res. 27: 1816-1829

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