
Fragile nucleosomes contain AT-rich, nucleosome disfavoring, and poorly conserved DNA. (A) Histogram of average GC content at fragile (green) or all nucleosomes (gray). (B) Same as A for resistant (orange) or all nucleosomes (gray). (C) Histogram of in vitro nucleosome occupancy scores at fragile or all nucleosomes. (D) Same as C for resistant nucleosomes or all nucleosomes. (E) Histogram of PhastCons seven-way conservation score at fragile or all nucleosomes. (F) Same as E for resistant or all nucleosomes.











