Transcriptomic and epigenetic features of Alu elements according to their expression levels in the HCT116 cell line. (A) Distribution of Alu repeats according to the expression levels in regard to DNA methylation, expression of the associated gene, and gene-related location. (B) Enrichment distribution of chromatin functional states in Alu elements according to their expression levels (top) and that of associated gene (middle) and the DNA methylation state. (C) Distribution of Alu repeats according to the expression levels, expression of the associated gene, and DNA methylation in regard to HMAR location. (D) Plotting of 9339 Alu repeats sorted according to their expression (purple dots) and nearest gene expression (black dots). Low DNA methylation state (green bars at the top) and HMAR location (red bars at the bottom) are indicated for each Alu.
