Identification of complex genomic rearrangements in cancers using CouGaR

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Figure 3.
Figure 3.

Distribution of multichromosome contigs. For each of the tumor types, we looked at the chromosomes that each of the contigs span and binned each sample based on the most chromosomes spanned by any contig. In the bar chart, we show the percentage of samples based on the contig with the largest number of chromosomes (1–9). For each cancer type, we also report as a fraction the number of samples with a contig spanning three or more chromosomes. We notice that prostate (PRAD) and bladder (BLCA) cancers have a high occurrence of multichromosome contigs. On the other end of the spectrum are colon (COAD) and rectal (READ) cancers, with most contigs contained in one chromosome.

This Article

  1. Genome Res. 27: 107-117

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