Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression

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Figure 4.
Figure 4.

Enrichment analysis of down- or up-regulated genes against sex-biased genes. Analysis was performed separately for down-regulated and up-regulated genes found in both hybrids against the gene categories defined by two previous studies (see text). Note a significant enrichment of spermatogenesis genes (A) or male-specific genes (B) in the down-regulated gene list. “Low male” category also shows a significant enrichment for up-regulated genes, but its ratio is not comparable to those in down-regulated list. (C) Gene ontology analysis of down- or up-regulated genes shared by the two sterile lines.

This Article

  1. Genome Res. 26: 1219-1232

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