SMARCA4 regulates gene expression and higher-order chromatin structure in proliferating mammary epithelial cells

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Figure 3.
Figure 3.

Genome-wide all-by-all Hi-C interaction heatmaps at 1-Mb resolution and a zoom-in of Chr 11 at 250-kb resolution (middle) and at 40-kb resolution (lower) in MCF-10A shSCRAM (A) and MCF-10A shSMARCA4 cells (B). For the genome-wide heatmaps, the chromosomes are stacked from top-left to bottom-right in order (Chr 1, Chr 2, …, Chr 22, and Chr X). The gray regions indicate repetitive regions (such as centromeres) in which the sequencing reads could not be mapped. The genomic compartments are shown below the middle heatmaps.

This Article

  1. Genome Res. 26: 1188-1201

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