Novel features of telomere biology revealed by the absence of telomeric DNA methylation

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Figure 9.
Figure 9.

Model representing the influence of DNA methylation on the homeostasis of telomere length. (A) The DNA methylation machinery of wild-type plants can target subtelomeric regions (gray bar) and telomere-subtelome junctions (dark gray bar) but not telomeres (black bar). In this scenario, subtelomeric DNA methylation contributes to positively regulate telomere length. (B) The homeostasis of telomere length is lost when subtelomeric DNA methylation cannot be achieved due to the impairment of the DNA methylation machinery.

This Article

  1. Published in Advance July 12, 2016, doi: 10.1101/gr.202465.115 Genome Res. 26: 1047-1056

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