
Expression by unique types of binding sites. Expression of CREs in the OSKE library with four total TFBS by the number of unique types of binding sites in the CRE (number of TFs for which binding sites are represented). Data are represented as box plots. Within the group with two unique types of binding sites, CREs with two sites of each type have higher expression than CREs with three sites of one type and one site of the other type (Supplemental Fig. S4).











