Differential expression variance within the sexes. (A) Comparison of genes with significant sex-specific expression variance (FDR 5%) and sex-specific expression (FDR 5%) on the autosomes and the X Chromosome in the DGN. To test for differences in mean expression and variance, the number of males and females were matched (n = 274). One-sided Fisher's exact test P-values above bars indicate significance of higher expression or variance on the X Chromosome relative to autosomes. (B) Proportion of variance explained (PVE) by genotype on the X Chromosome in males and females. To test for the PVE, the number of males and females were matched (n = 274). We tested all genes on the X Chromosome and genes with a cis-eQTL (Bonferroni adjusted P-value < 0.05).
