Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters

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Figure 6.
Figure 6.

Regulatory properties of active promoters in IMR90 cells using 18 histone acetylation profiles and Hi-C data. (A) Clustering of RefSeq promoters by IMR90 histone modification profiles: iP1-iP7 classes identified de novo from this data set match P1–P7 classes in Figure 4. (B) Absolute expression and DNase hypersensitivity for each of the seven IMR90 promoter classes. (C) Cell-type-specific expression. (D) Number of enhancer–promoter connections (Hi-C) for each of the seven IMR90 promoter classes.

This Article

  1. Published in Advance March 8, 2016, doi: 10.1101/gr.201038.115 Genome Res. 26: 612-623

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