Segregation of the parental genomes in distinct cell lineages following dispermic fertilization. (A) Genome-wide paternal and maternal haplarithms reveal dispermic fertilization and maternal MII triploidy (consult also the digynic haplarithm profile in Fig. 3A). Blastomere 2 (top) is androgenetic. This paternal genome is absent from the triploid blastomere (bottom, Bl005) as different paternal genome-wide HR-sites were detected in this cell. Note that here, option 2 of siCHILD (see Methods) was applied as an expanded blastocyst was used for phasing the parental genomes. (B) Circos plot illustrating the genome-wide interpreted copy-number profiles of all the single blastomeres derived from embryo E12_BRP010.
