Figure 3.
Frequency of the mutant allele (relative to the revised Cambridge Reference Sequence [rCRS]) and frequency change of the mutant allele for different mutation types. (A) Frequency of the mutant allele for: NS mutations in the mother [NS(M)]; SS and NC mutations in the mother [SS-NC(M)]; NS mutations in the offspring [NS(O)]; and SS and NC mutations in the offspring [SS-NC(O)]. (B) Distribution of the frequency change of NS and SS-NC mutations during transmission from mothers to offspring. The same results were obtained when the analyses were done for the minor allele at each position rather than the non-rCRS allele.
