Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation

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Figure 8.
Figure 8.

Defects in promoter H3 eviction are associated with marked reductions in Pol II levels only for the most highly expressed subset of genes. (A,B) Median relative H3 occupancies per base pair in the [−1,NDR,+1] regions (A) or median log2 values of Rpb3I occupancies per base pair in CDS (B) for the 70 exemplar genes or for each Rpb3 decile. The 4744 genes not appreciably induced by SM were divided into 10 deciles according to Rpb3 occupancies in SM-induced WT cells.

This Article

  1. Genome Res. 26: 211-225

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