Quantification of in vivo progenitor mutation accrual with ultra-low error rate and minimal input DNA using SIP-HAVA-seq

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Figure 5.
Figure 5.

Graphical overview of sequencing results and detected mutations. Densities of DNA-seq Q2 candidates with at least one Q1/Q2 candidate at a matching position in the sister sample, RNA-seq duplex coverage, gene regions, and duplex disagreements are shown on outer tracks. Detected mutations, color-coded by kind, sample type (mated or unmated), and location type (gene or nongene) are shown as bars.

This Article

  1. Genome Res. 26: 1600-1611

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