Carole Charlier; Wanbo Li; Chad Harland; Mathew Littlejohn; Wouter Coppieters; Frances Creagh; Steve Davis; Tom Druet; Pierre Faux; François Guillaume; Latifa Karim; Mike Keehan; Naveen Kumar Kadri; Nico Tamma; Richard Spelman; Michel Georges

NGS-based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock

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Figure 1.

(A,B) Number of heterozygous synonymous (gray) and nonsynonymous (yellow) sites per individual (A: humans; B: bovine). (C,D) Number of heterozygous stop-gain (squares), splice-site (triangles), and frame-shift (circles) sites per individual. CHB: Chinese; JPT: Japanese; FIN: Finns; GBR: Britons; CEU: Northern Europeans; YRI: Yorubans; ANG: Angus; BBB: Belgian Blue; CHA: Charolais; HOL: Holstein-Friesian; JER: Jerseys; SIM: Simmentals.