Dot-plots illustrate the pattern of the rearrangements observed for six SCRaMbLE strains. In each case, the order of segments in the SCRaMbLE strain (y-axis) is compared with the parental order (x-axis), with orientation either the same (black dot) or inverted (blue dot). (A) Simple deletions in JS629 create gaps. (B) Inversions in JS738 appear as blue stripes perpendicular to the main diagonal. (C) Tandem duplications in JS621 create parallel stripes. (D) Inverted duplications in JS614 create alternating perpendicular and parallel stripes. (E,F) Increasingly complicated patterns in JS735 and JS710 arise from recombination events within previous events, particularly when duplications are already present.
