SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

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Figure 2.
Figure 2.

Rearrangements were observed in synIXR SCRaMbLE strains. Each SCRaMbLE strain is represented as a sequence of arrows. The color of each arrow indicates the segment number in the parental chromosome, and the direction of the arrow represents the orientation (SCRaMbLEgram visualization). A red border denotes a segment containing an essential gene. The names of slow growth strains are indicated in red text.

This Article

  1. Published in Advance November 13, 2015, doi: 10.1101/gr.193433.115 Genome Res. 26: 36-49

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