RNA structure replaces the need for U2AF2 in splicing

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Figure 2.
Figure 2.

AC and GT repeats co-occur across introns, not exons. Zebrafish introns containing AC repeats within 200 nt of the 5′ ss were examined for downstream intron GT repeats (left panel) or upstream intron repeats (right panel). Introns were binned according to the length of the GT repeats (# of repeats, x-axis) and AC repeats (# of repeats, y-axis). The observed frequency of introns with each combination of repeat length is shown on the graph. The heat map color of each bin indicates the fold difference of observed frequency over the co-occurrence frequency predicted by a model of independently distributed AC and GT repeats.

This Article

  1. Genome Res. 26: 12-23

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