RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

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Figure 6.
Figure 6.

Insertion-modified transcripts (IMTs) in osteosarcoma tumors. Examples of increased IMTs via transcriptional activation for (A) Cngb3, (B) Poln, and (C) Braf, and for decreased IMTs with apparent activation of opposite strand transcript (D) Cdc42, (E) Xpo4, and (F) Max. FPKM, locations of reLM-PCR junction fragments and fusion products are shown as described for Figure 1.

This Article

  1. Published in Advance November 9, 2015, doi: 10.1101/gr.188649.114 Genome Res. 26: 119-129

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