Figure 3.
Identification of ESC-associated lncRNAs. (A) Heatmap (GeneWise Z-score) of the 50 lncRNAs most specifically (calculated based on Z-score) expressed in ESCs at ≥1 FPKM. ENCODE mouse tissue poly(A)+ RNA-seq data represent the average expression of two biological replicates. (B) Expression heatmap of the gene module containing Pou5f1 as determined by weighted gene coexpression analysis. (C) Gene ontology (GO) terms for biological process selected from the top 20 nonredundant terms enriched in the Pou5f1 gene module. Enrichment was ranked based on Fisher's exact test.
