Relationships between nucleosome occupancy and gene expression. (A) Nucleosome occupancy profiles in regions flanking the transcription start site (TSS, left) and transcription termination site (TTS, right) of protein coding genes with different transcript levels (expression percentile in which the 0–10 category includes genes with the lowest expression level): (NOC) median nucleosome occupancy score of genes per base. (B) Regression coefficient of a linear regression model for gene expression prediction using nucleosome occupancy in 100-bp bins flanking TSS (left) and TTS (right) as predictors: (R2) coefficient of determination of the overall model; (error bars) the 5th and 95th confidence interval. (C) Same as B, except that naked gDNA data were used.
