Genome-wide activities of Polycomb complexes control pervasive transcription

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Figure 5.
Figure 5.

H3K27ac and H3K4me1 levels increase upon E(z) inactivation. (A,B) H3K27ac and H3K4me1 in intergenic regions were assayed by ChIP-qPCR in EZ2-2 cells at 25°C and 31°C. (C) Box plots of H3K27ac levels in non-PcG targets with different expression levels and PcG targets at 25°C and 31°C. (D,E) The increase in H3K27ac and H3K4me1 levels after E(z) inactivation is negatively correlated with those levels at 25°C. The ratio of levels at 31°C and 25°C was calculated for non-PcG target genes with different levels at 25°C.

This Article

  1. Published in Advance May 18, 2015, doi: 10.1101/gr.188920.114 Genome Res. 25: 1170-1181

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