Figure 4.
Attenuation of intergenic derepression by depletion of Trithorax group proteins. Expression levels in a panel of intergenic regions were measured by RT-qPCR analysis with total RNA from EZ2-2 cells at 25°C and 31°C incubated with dsRNA targeting LacZ (mock treatment), Utx (A), trr (C), or CBP (E) for 12 d. The expression levels are normalized by the DNA amount in input cells. (B,D,F) The efficiency of the knockdown experiments was monitored by the mRNA levels of the targets.
