An efficient and scalable analysis framework for variant extraction and refinement from population-scale DNA sequence data

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Figure 6.
Figure 6.

Comparison of known and novel Ts/Tv with and without trimming overlapping reads for 1000 low-coverage Chromosome 20 sequences from the 1000 Genomes Project. Overlapping fragments lowers novel Ts/Tv and the effect is more eminent in the singletons (with allele count of one).

This Article

  1. Published in Advance April 16, 2015, doi: 10.1101/gr.176552.114 Genome Res. 25: 918-925

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