Figure 4.
Monomeric GR colocalizes with lineage-determining TFs in liver. (A) HOMER de novo motif analyses for the dimeric and monomeric GR binding sites from liver ChIP-seq. The four top-ranked lineage TF motifs are shown relative to the top-ranked GR sequence. See Supplemental Material for a comprehensive list of motifs. (B) Box plots interrogating the co-occupancy of liver TFs at GR binding sites. (C) Distribution of dimer and monomer GR binding sites relative to colocalized HNF4A, CEBPB, ONECUT1, and/or FOXA2. All TF combinations were examined.
