Characteristics of de novo structural changes in the human genome

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Figure 4.
Figure 4.

Mechanisms contributing to the formation of de novo SVs. (A) Overview of four SV formation mechanisms, including examples and observed counts for each of these. (L) Left flank, (R) right flank, (J) junction. (B) Schematic structure of a complex de novo interchromosomal SV involving an insertion of DNA from Chromosomes 3 and 19 into Chromosome 4. (TSD) Target site duplication.

This Article

  1. Published in Advance April 16, 2015, doi: 10.1101/gr.185041.114 Genome Res. 25: 792-801

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