Characterizing and controlling intrinsic biases of lambda exonuclease in nascent strand sequencing reveals phasing between nucleosomes and G-quadruplex motifs around a subset of human replication origins

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Figure 4.
Figure 4.

Distribution of G4 motifs around peak summits. (Left) The distributions of G4 motifs (non-strand-oriented) around LexoG0G0gDNA (A), NSG0gDNA (C), and NSLexoG0 (E) peak summits. The red lines indicate the positions of wave crests; labeled arrows, the distance between adjacent crests. (Right) The distributions of G4 motifs (strand oriented 5′-3′ left to right) around LexoG0G0gDNA (B), NSG0gDNA (D), and NSLexoG0 (F) peak summits.

This Article

  1. Published in Advance February 18, 2015, doi: 10.1101/gr.183848.114 Genome Res. 25: 725-735

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