New signaling pathways govern the host response to C. albicans infection in various niches

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Figure 4.
Figure 4.

PDFGRB and NEDD9 mediate endocytosis of C. albicans by host cells. Effects of siRNA knockdown of PDGFRB or NEDD9 on endocytosis of C. albicans by endothelial cells (A) and oral epithelial cells (B). The effect of pharmacological inhibition of the PDGF receptor on endocytosis by endothelial cells (C) and oral epithelial cells (D) was also tested. Results are the mean ± SD of three experiments, each performed in triplicate. (*) P < 0.00003 versus controls; n = 12 from four independent experiments.

This Article

  1. Published in Advance April 9, 2015, doi: 10.1101/gr.187427.114 Genome Res. 25: 679-689

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