Figure 3.
Mitochondrial contribution to variability in translation. Mitochondrial contribution to variability in translation factors. (A) Yellow bars are elongation translation factors. (B) Heterogeneity in ribosomes and ribosome apparatus synthesis. YOYO-1 stain is specific for double-stranded RNA, which is almost exclusive of ribosomes. UBTF evidences ribosome biosynthesis, and NCL and NPM1 are involved in ribosome maturation. (C) Variability induced by mitochondria in protein synthesis: (red bars) nascent protein as measured by the precursor AHA, and activated protein synthesis, P-RPS6.
