Evidence for widespread subfunctionalization of splice forms in vertebrate genomes

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Figure 6.
Figure 6.

Structural evidence of splice form subfunctionalization. The zebrafish paralogs cnnm2a and cnnm2b correspond to distinct isoforms of the alternatively spliced orthologous human gene CNNM2. The dashed box highlights the alternatively spliced cassette exon from the human gene that has been subfunctionalized in the zebrafish paralogs. The dashed lines connect homologous exons. Exons lengths are indicated either below or above exons. Introns are not to scale.

This Article

  1. Genome Res. 25: 624-632

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