A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

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Figure 1.
Figure 1.

Phenotypic analysis of the TF library by MS1096-Gal4–driven expression in the developing wing. Phenotypes upon misexpression by MS1096-Gal4 (black bars) are compared to RNAi knockdown (gray bars) and two other misexpressed gene sets: cell cycle regulators (white bars) and miRNAs (green bars). Phenotypic strength was recorded from no effect, weak growth, or patterning defects (+) to severe size or patterning defects (++), almost complete absence of wings (+++) to lethality (lethal); bars show the distribution of observed phenotypes for each data set. Representative examples for the phenotypes (+ to +++) are shown. Arrowheads point to patterning defects.

This Article

  1. Genome Res. 25: 514-523

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