DNA methylation at hepatitis B viral integrants is associated with methylation at flanking human genomic sequences

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Figure 2.
Figure 2.

Distribution of the integration sites in the HBV genome and human chromosomes represented by Circos plots of the PLC/PRF/5 genome and the HepG2.2.15 genome. HBV DNA integration was analyzed using the G-NaVI method in the genome of PLC/PRF/5 cells and HepG2.2.15 cells. A common HBV integration site was not detected. Integration sites were not detected in exonic regions of the DNA from cell lines (Venn diagrams). The HBV genes (PreC, Precore; C, Core; PreS, Presurface; S, Surface; X, X) and the 24 human chromosomes are shown.

This Article

  1. Published in Advance February 4, 2015, doi: 10.1101/gr.175240.114 Genome Res. 25: 328-337

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