Epigenetic marks and contact strength. (A) Comparison of CS and contact strength across 2-kb bins graphed according to the first three principal components for epigenetic marks (similar to Fig. 2C). Contact strength is the sum of contacts of a 2-kb bin with the 10 surrounding bins. “Unclear” indicates no enrichment for any epigenetic mark. (B) Contact strengths of bins according to CS classification. CS3 and CS4 are shaded, as their sequences display biases that might result in lower contact strength values. (C) CS classification of bins ranked by contact strength, from low to high. (D) Contact strength of adjacent bins. In C,D, due to biases, data regarding CS3 and CS4 are not shown, but they are presented in Supplemental Figure 12. In B–D, the few bins of unclear categorization are not shown.
