Figure 3.
Jα-Jα ECs occur predominantly with their nearest neighbor. (A) Graphical representation of individual Jα-Jα ECs from a whole thymus EC-seq library showing connectivity and relative frequency of Jα-Jα ECs across the Jα element subregion. Ribbon width represents the frequency of recombinations between connected segments. Ribbon color is alternated to discriminate between independent ribbon connections at the same segment. (B) Heatmap meta-analysis of 33,332 Jα-Jα RFs showing the frequency of individual EC events. (C) Jα-Jα EC events from thymic and splenic EC-seq libraries showing the frequency of excisions spanning neighboring or multiple genomic Jα segments.
