Figure 2.
Vervet chromosomes showing synteny breakage with respect to rhesus macaque. (A) On each vervet chromosome, on the right, the corresponding human synteny blocks are reported and also colored for ease of interpretation. Black arrows indicate an identical sequence orientation; red arrows indicate inverted orientation. “ENC” denotes the approximate location of evolutionary neocentromeres. (B) FISH results using RP11-450M18, RP11-435K10, and RP11-1115K14 human BACs (mapping on Chromosome 5) to homologous chromosomes of rhesus macaque and vervet (see Methods).
