DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts

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Figure 6.
Figure 6.

The relationship between PAR-CLIP signals and mRNA, PROMPTs, snoRNA precursors, and intron 1 expression changes in DIS3 double mutants. The PAR-CLIP signal was defined as PAR-CLIP RPKM divided by RNA-seq RPKM in WT cells. Transcripts with no PAR-CLIP signal were not included in this plot. Data for the first intron are only from transcripts that show up-regulation of the first intron in double mutants but not for the second intron.

This Article

  1. Published in Advance August 20, 2015, doi: 10.1101/gr.189597.115 Genome Res. 25: 1622-1633

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